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Selection. Taken together, we conclude from our data that the Roc NH2-terminal b-strand makes a relatively stronger contribution to Cullin binding preference than the RING domain. The lethality of Roc1a mutants is presumably caused by the inappropriate accumulation of at least one target of a Roc1acontaining Cullin dependent E3 ligase [24]. The ANBR protein cannot rescue the lethality of Roc1a mut
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Essor of Physiology, Faculty of Science, Ain Shams University for his kind support and guidance throughout this work and for providing the necessary funding and laboratory facilities.20. 21. 22.Tong et al. BMC Endocrine Disorders 2010, 10:4 http://www.biomedcentral.com/1472-6823/10/RESEARCH ARTICLEOpen AccessEarly limited nitrosamine exposures exacerbate high fat diet-mediated type 2 diabete
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Essor of Physiology, Faculty of Science, Ain Shams University for his kind support and guidance throughout this work and for providing the necessary funding and laboratory facilities.20. 21. 22.Tong et al. BMC Endocrine Disorders 2010, 10:4 http://www.biomedcentral.com/1472-6823/10/RESEARCH ARTICLEOpen AccessEarly limited nitrosamine exposures exacerbate high fat diet-mediated type 2 diabete
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Essor of Physiology, Faculty of Science, Ain Shams University for his kind support and guidance throughout this work and for providing the necessary funding and laboratory facilities.20. 21. 22.Tong et al. BMC Endocrine Disorders 2010, 10:4 http://www.biomedcentral.com/1472-6823/10/RESEARCH ARTICLEOpen AccessEarly limited nitrosamine exposures exacerbate high fat diet-mediated type 2 diabete
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